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Showing posts with the label hemorrhagic fever

What is The Marburg Virus and How Dangerous is it

Marburg virus is a highly virulent, hemorrhagic fever-causing virus belonging to the Filoviridae family, which also includes the Ebola virus. Marburg virus was first identified in 1967, when outbreaks occurred simultaneously in Marburg and Frankfurt, Germany, and in Belgrade, Yugoslavia, among laboratory workers who had come into contact with infected African green monkeys imported from Uganda. Transmission and Pathogenesis: The natural reservoir of Marburg virus is believed to be fruit bats of the Pteropodidae family, which are found in parts of Africa. Human infections occur through direct or indirect contact with infected bats, primates, or other infected humans. Once the virus enters the body, it replicates in the mononuclear phagocytic system, including macrophages and dendritic cells. The virus then spreads throughout the body via the bloodstream, causing damage to multiple organs, including the liver, spleen, and lymph nodes. Clinical Manifestations: Marburg virus infect...